The fifth edition of EPAS covers the five-year period between 2016 and 2020 and is now an integral part of the Agency's programming activities. This means that the safety priorities identified in EPAS are addressed by specific actions in the Agency's rulemaking or safety promotion programmes, specific actions in the State Safety Programmes (SSPs) or through focused oversight activities performed either by the Agency or the MS. In comparison with previous editions, the current one is more data driven, providing a clear link with the Annual Safety Review (ASR) and with the Agency's Rulemaking Programme. An increased emphasis has been put on using safety promotion and focused oversight activities to mitigate safety risks. In terms of content, EPAS contains three categories of safety issues: systemic, operational and emerging.